Aptamer 学术简报 — neurodegeneration — 2026-09-24
自动生成 by RBTX Aptamer Tracker v0.1。 子主题 neurodegeneration:近 14 天 2 篇命中(aptamer 池 124 篇)。
评分公式:composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus;满分 100。
#1 [11.2] Aptamer-Based Heterobifunctional Targeted Degraders in Disease Treatment
- Journal: Molecules (IF 4.2)
- Date: 2026-09-18 · Citations: 0
- Authors: Xiuhua Liang, Menghan Du, Jing Wang et al. (6 authors)
- DOI: 10.3390/molecules31183318
- Score components: IF 7.2 · recency 80.0
Aptamers are short nucleic acid molecules that bind to targets with high specificity. Recognized as “chemical antibodies”, they offer distinct advantages including strong programmability and ease of synthesis and chemical modification. Heterobifunctional targeted degraders were developed to address the challenges posed by traditionally “undrugga...
#2 [10.8] Split malachite green aptamer transcription-based AND logic fluorescent platform: A novel approach for dual-miRNA detection in diabetes mellitus complicated with Alzheimer's disease
- Journal: Microchemical Journal (IF 4.9)
- Date: 2026-09-16 · Citations: 0
- Authors: Ji Chen, Lumiao Liao, Hongming Lu et al. (8 authors)
- DOI: 10.1016/j.microc.2026.119722
- Score components: IF 7.7 · recency 73.3
Methodology
- 数据源:PubMed (esearch + esummary), OpenAlex (concept C2776201186 + DOI 反查 citations), bioRxiv (preprints)
- 去重:按 DOI 跨源合并
- IF:硬编码 top 50 期刊 JCR 2024 IF(
config.JOURNAL_IF) - Citation velocity:OpenAlex
cited_by_count/ 发表天数 - Social:Reddit r/science + r/biotech + HN(DOI/title 关键词搜)
- 窗口:近 14 天发表;超出 30 天 recency_bonus = 0
- 每天:建议 8-9am 跑
python run.py collect && python run.py score && python run.py report