Aptamer 学术简报 — neurodegeneration — 2026-09-22
自动生成 by RBTX Aptamer Tracker v0.1。 子主题 neurodegeneration:近 14 天 3 篇命中(aptamer 池 130 篇)。
评分公式:composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus;满分 100。
#1 [11.5] Split malachite green aptamer transcription-based AND logic fluorescent platform: A novel approach for dual-miRNA detection in diabetes mellitus complicated with Alzheimer's disease
- Journal: Microchemical Journal (IF 4.9)
- Date: 2026-09-16 · Citations: 0
- Authors: Ji Chen, Lumiao Liao, Hongming Lu et al. (8 authors)
- DOI: 10.1016/j.microc.2026.119722
- Score components: IF 7.7 · recency 80.0
#2 [8.4] Preliminary Development of a Hybrid Aptamer and Antibody Fluorescent Lateral Flow Assay for Ultrasensitive Detection of Tau441 Protein in Serum: Toward Point-of-Care Diagnostics for Alzheimer's Disease.
- Journal: Journal of fluorescence (IF 3.0)
- Date: 2026-09-09 · Citations: 0
- Authors: Mahrat R, Chen Y, Bruno JG et al. (6 authors)
- DOI: 10.1007/s10895-026-04925-y · PMID: 42711626
- Score components: IF 6.0 · recency 56.7
A hybrid DNA aptamer and antibody-Europium nanoparticle (Eu NP) fluorescent sandwich lateral flow (LF) assay for Tau441 is described which works well in human serum with an apparent visible detection limit for Tau 441 of ~ 10 pg/ml or 1 pg of Tau protein. The same LF assay appears to detect phosphorylated threonine 217 Tau 441 (phospho Thr-217 T...
Methodology
- 数据源:PubMed (esearch + esummary), OpenAlex (concept C2776201186 + DOI 反查 citations), bioRxiv (preprints)
- 去重:按 DOI 跨源合并
- IF:硬编码 top 50 期刊 JCR 2024 IF(
config.JOURNAL_IF) - Citation velocity:OpenAlex
cited_by_count/ 发表天数 - Social:Reddit r/science + r/biotech + HN(DOI/title 关键词搜)
- 窗口:近 14 天发表;超出 30 天 recency_bonus = 0
- 每天:建议 8-9am 跑
python run.py collect && python run.py score && python run.py report