Aptamer 学术简报 — neurodegeneration — 2026-09-21

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 neurodegeneration：近 14 天 3 篇命中（aptamer 池 137 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [8.7] High-Performance Screen-Printed OECT-Inspired with Encased Cassette Based on PEDOT:GO for Sensitive and Specific Electrochemical Aptasensing of Aβ-42 in Management of Alzheimer's Disease.

Recently, substantial interest has emerged in developing point-of-care diagnostic devices for Alzheimer's disease (AD), a progressive neurodegenerative disorder characterized by the accumulation of beta-amyloid (Aβ1-42) peptides that act as critical biomarkers for early detection. In response to the growing demand for noninvasive and accessible ...

#2 [8.7] Preliminary Development of a Hybrid Aptamer and Antibody Fluorescent Lateral Flow Assay for Ultrasensitive Detection of Tau441 Protein in Serum: Toward Point-of-Care Diagnostics for Alzheimer's Disease.

A hybrid DNA aptamer and antibody-Europium nanoparticle (Eu NP) fluorescent sandwich lateral flow (LF) assay for Tau441 is described which works well in human serum with an apparent visible detection limit for Tau 441 of ~ 10 pg/ml or 1 pg of Tau protein. The same LF assay appears to detect phosphorylated threonine 217 Tau 441 (phospho Thr-217 T...

Methodology