Aptamer 学术简报 — neurodegeneration — 2026-09-04

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 neurodegeneration：近 14 天 4 篇命中（aptamer 池 229 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [12.5] Photoelectrochemical highly efficient detection of β-amyloid 1-42 based on in-situ grown donor-acceptor covalent organic frameworks combined with dual-aptamer sandwich amplification strategy.

A highly sensitive dual-aptamer sandwich-type photoelectrochemical (PEC) sensor was developed for detecting β-amyloid 1-42 (Aβ42), whose abnormal accumulation in the brain has been considered as the molecular driver of Alzheimer's (AD) pathogenesis and progression. The sensor was constructed based on in-situ grown covalent organic frameworks (CO...

#2 [10.6] Antibodies and aptamers as affinity ligands for exosome isolation, detection, and targeted delivery: A review.

Exosomes, key mediators of intercellular communication, are emerging as promising tools for disease diagnosis and therapy. Realizing this potential depends on technologies that can isolate, detect, and deliver exosomes with high specificity and efficiency. Affinity-based strategies that exploit the molecular recognition of antibodies and aptamer...

#3 [9.8] Aptamer-Based Platforms for Human Aging Biomarkers: Multiplexed Proteomics, Biosensors and Translational Perspectives

Aptamer-based multiplexed proteomic platforms, especially the SOMAmer-based SomaScan assay, are widely used for large-scale discovery of circulating biomarkers relevant to human aging. This review summarizes 42 original research articles published from 2020 through 2026 in which aptamers or aptamer-derived biosensors were used to characterize ag...

Methodology