Aptamer 学术简报 — neurodegeneration — 2026-08-26

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 neurodegeneration：近 14 天 7 篇命中（aptamer 池 196 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [15.2] Steric hindrance effect synergizing hole-trapping technique: High-Stability and high-accuracy Si/CdS n-n heterojunction photoelectrochemical biosensing of amyloid-β42.

Due to rapid carrier recombination and photodegradation, cadmium sulfide (CdS), an n-type semiconductor photosensitive material, has a low utilization efficiency that restricts its use in biosensing. A synergistic hole-trapping approach utilizing steric hindrance effects is proposed in this paper. First, chemical bath deposition (CBD) is used to...

#2 [13.6] Antibodies and aptamers as affinity ligands for exosome isolation, detection, and targeted delivery: A review.

Exosomes, key mediators of intercellular communication, are emerging as promising tools for disease diagnosis and therapy. Realizing this potential depends on technologies that can isolate, detect, and deliver exosomes with high specificity and efficiency. Affinity-based strategies that exploit the molecular recognition of antibodies and aptamer...

#3 [12.8] Aptamer-Based Platforms for Human Aging Biomarkers: Multiplexed Proteomics, Biosensors and Translational Perspectives

Aptamer-based multiplexed proteomic platforms, especially the SOMAmer-based SomaScan assay, are widely used for large-scale discovery of circulating biomarkers relevant to human aging. This review summarizes 42 original research articles published from 2020 through 2026 in which aptamers or aptamer-derived biosensors were used to characterize ag...

#4 [12.8] A bioelectronic interface for continuous neuroinflammation monitoring and neuromodulation in Parkinson's disease model.

Neuroinflammation is increasingly recognized as a critical driver in the onset and progression of Parkinson's disease (PD), yet technologies capable of continuously tracking neuroinflammatory dynamics in vivo remain limited. Here, we report an implantable bioelectronic interface that integrates multiplexed aptamer based electrochemical biosensin...

#5 [12.2] Author Correction: Circular RNA aptamers targeting neuroinflammation ameliorate Alzheimer disease phenotypes in mouse models.

#6 [9.8] Label-free electrochemical aptasensor for sensitive and selective recognition of N(6)-Methyladenosine: Applicability in human urine.

The specific and accurate detection of ultra-low levels of N6-methyladenosine (m6A) in biological samples holds great potential in the clinical diagnosis of various cancer types and neurodegenerative diseases. In this study, a cost-effective, label-free electrochemical aptasensor was developed by self-assembling a thiol-modified aptamer onto the...

#7 [9.1] High-Performance Screen-Printed OECT-Inspired with Encased Cassette Based on PEDOT:GO for Sensitive and Specific Electrochemical Aptasensing of Aβ–42 in Management of Alzheimer’s Disease

Abstract Recently, substantial interest has emerged in developing point-of-care diagnostic devices for Alzheimer's disease (AD), a progressive neurodegenerative disorder characterized by the accumulation of beta-amyloid (Aβ1−42) peptides that act as critical biomarkers for early detection. In response to the growing demand for noninvasive and ac...

Methodology