Aptamer 学术简报 — neurodegeneration — 2026-08-06

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 neurodegeneration：近 14 天 4 篇命中（aptamer 池 190 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [5.3] Aptamer-Based Detection of Chronic Traumatic Encephalopathy Predictive Biomarker S100B Using Laser Wave-Mixing Detection Coupled with Capillary Electrophoresis

Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease associated with repetitive head trauma, for which there is currently no well-established antemortem diagnostic biomarker. In this report, a proof-of-concept experiment is described for conditions optimized for the selection and detection of aptamers against S100B, ...

#2 [5.3] Exosome-Mediated Drug Delivery: Emerging Opportunities in Cancer, Neurodegenerative Disorders, and Personalized Medicine

Exosomes are nanoscale, cell-derived membrane vesicles that mediate intercellular communication by transferring proteins, lipids, and nucleic acids between donor and recipient cells. Because they are biocompatible, exhibit low intrinsic immunogenicity, can be engineered for tissue-specific targeting, and are capable of crossing biological barrie...

#3 [5.3] Exosome-Mediated Drug Delivery: Emerging Opportunities in Cancer, Neurodegenerative Disorders, and Personalized Medicine

Exosomes are nanoscale, cell-derived membrane vesicles that mediate intercellular communication by transferring proteins, lipids, and nucleic acids between donor and recipient cells. Because they are biocompatible, exhibit low intrinsic immunogenicity, can be engineered for tissue-specific targeting, and are capable of crossing biological barrie...

#4 [5.3] SMART-NeuroDx: A Reagent-Free Multianalyte Biosensor Platform with Machine-Learning Readout for Point-of-Care Dementia Screening

Differentiating overlapping dementia pathologies, such as frontotemporal dementia and Alzheimers disease, calls for the simultaneous measurement of several blood biomarkers, yet electrochemical sensors remain predominantly single-target and dependent on labels and sample preparation. Here we report SMART-NeuroDx, a reagent-free electrochemical a...

Methodology