Aptamer 学术简报 — infectious_disease — 2026-07-04

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 infectious_disease：近 14 天 16 篇命中（aptamer 池 215 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [12.7] Quo Vadis, Electrochemical DNA Biosensor? Lessons from Three Decades of SNP Sensing.

Electrochemical DNA biosensors have been studied for over three decades, producing thousands of publications and a sophisticated engineering toolkit. However, a broad clinical adoption remains limited. The COVID-19 pandemic served as a stress test-global demand, unprecedented funding, accelerated regulatory pathways, and a clearly defined genomi...

#2 [12.3] Aptamer-powered surveillance of SARS-CoV-3.

Rapid detection of emerging coronaviruses is critical for preparedness. The S2A2C1 aptamer broadly recognizes Beta-coronavirus S2 domains but not influenza proteins. A sandwich aptamer assay achieved ∼0.51 pM detection limits and functions in serum, enabling a sensitive, adaptable platform for universal coronavirus detection and real-time survei...

#3 [11.7] Viral Membrane-Targeting Amphipathic Helical Peptide Ligands for Colorimetric Sandwich Assays of Influenza A Virus Particles.

Viral membrane-binding amphipathic helical (AH) peptides were explored as detection ligands in the sandwich-type colorimetric assay for selective detection of target influenza A virus (IAV) particles, combined with DNA aptamer-mediated capturing on a microplate. A truncated AH peptide from the C-terminal of apolipoprotein A-I (trApoC) was conjug...

#4 [9.7] The development of aptamer-functionalized streptavidin magnetic particles for sample purification of SARS-CoV-2 coupled with rapid plasmonic RT-qPCR to improve detection sensitivity.

Despite having endured numerous pandemics throughout history and contemporary technological advancements, the world was still unprepared for the emergence of the SARS-CoV-2 pathogen. Prior to the development and distribution of effective vaccines, health officials relied heavily on diagnostics to contain the spread of the virus. Reverse transcri...

#5 [9.0] Recombinant Taq DNA polymerase.

The sudden COVID-19 pandemic highlights the importance of diagnostic assays in health security readiness. One persistent difficulty is the rapid molecular detection of pathogenic microorganisms and viruses. Taq DNA polymerase remains an essential component for COVID-19 molecular detection. Taq DNA polymerase exhibits a high level of thermostabil...

#6 [8.3] Polyaniline metal dichalcogenide-based amplified aptasensor for SARS-CoV-2 spike glycoprotein detection in wastewater

The significance of nanocomposites (NCs) in the academic and industrial fields has been of great focus due to the combination of various qualities of different nanomaterials, with the aim of achieving controlled properties. In this work, the aptasensor fabrication consists of a SARS-CoV-2 spike glycoprotein specific thiolated aptamer (HS-Apt) im...

#7 [7.3] Electrochemical and optical biosensors as transformative tools for multiplex detection of influenza viruses.

The influenza viruses (IVs) are major public health risk, causing immense seasonal infections, severe illness, and respiratory deaths yearly. Rapid, accessible, and precise detection is essential because the IV RNA genome facilitates genetic recombination and rapid mutation, potentially leading to new pandemic strains that evade existing diagnos...

#8 [7.3] BIRD-Seq: B2 Protein Integrated End-to-End Pipeline for dsRNA Detection and Nanopore Sequencing for Virus Monitoring

Abstract Double-stranded RNA (dsRNA) is a near-universal hallmark of active viral infection. Despite its role as a pan-viral replication intermediate, dsRNA-centred technologies for virus monitoring remain scarce and largely rely on monoclonal antibody-based approaches that, while highly sensitive, are costly and difficult to engineer, scale, or...

#9 [7.0] Bioelectrochemical Sensing Dynamics of SARS-CoV-2 Biomarkers.

The SARS-CoV-2 outbreak has underscored the urgent need for rapid, sensitive and accessible diagnostic technologies. This review provides a comprehensive overview of recent advances in nucleic acid- and antibody-based bioelectrochemical detection strategies for SARS-CoV-2, targeting the nucleocapsid (N) protein, spike (S) protein, the receptor b...

#10 [7.0] A bifunctional aptamer-siRNA chimera targeting ACE2 for the inhibition of SARS-CoV-2 S pseudovirus entry and replication.

The relentless evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the emergence of immune-evasive variants underscore an urgent need for novel therapeutic strategies that are resilient to viral mutations. Targeting conserved host factors essential for viral entry represents a promising approach to overcome this challen...

Methodology