Aptamer 学术简报 — food_safety — 2026-09-30

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 food_safety：近 14 天 24 篇命中（aptamer 池 173 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [14.1] A dual-mode electrochemical-colorimetric aptasensor based on HCR-CRISPR/Cas12a cascade amplification for MTGase detection.

Microbial transglutaminase (MTGase) is widely used in food processing, but its potential food safety risks cannot be neglected. MTGase-treated wheat products show immunoreactivity, which may induce celiac disease and damage intestinal barrier function. Therefore, trace detection of MTGase is of great significance. In this study, an electrochemic...

#2 [12.9] Target-sensitive aptasensor FRET readout using a fluorescent nucleobase surrogate for detection of ochratoxin A.

A target-sensitive FRET aptasensor platform is reported for ochratoxin A (OTA) detection. The intrinsic emission of OTA serves as the FRET donor to an internal fluorescent merocyanine nucleobase FRET acceptor. The platform achieves low nanomolar sensitivity and high selectivity over the nonchlorinated ochratoxin B (OTB) through binding-generated...

#3 [12.8] Mechanistic insights into graphene quantum dots-mediated regulation of single-atom nanozyme activity for homogeneous dual-mode detection of acetamiprid.

A homogeneous colorimetric/ratiometric fluorescence biosensor was developed for acetamiprid (Ace) detection based on graphene quantum dots (GQDs)-regulated Fe/Mn-N-C single-atom nanozyme (SAzyme) activity. Aptamer-functionalized SAzymes with high peroxidase-like activity were hybridized with complementary DNA-modified GQDs (CS/GQDs) emitting flu...

#4 [12.4] Ratiometric Fluorescence Sensing of Aflatoxin B1 Using a Cationic Perylene Probe and Rhodamine B.

As one of the most toxic and prevalent mycotoxins, aflatoxin B1 (AFB1) poses a persistent threat to food safety and public health due to its widespread contamination of cereal commodities and its well-documented carcinogenic, genotoxic, and hepatotoxic effects. Although fluorescence sensing provides a rapid approach to AFB1 screening, most exist...

#5 [11.5] Hierarchical magnetic nano-orb-assisted fluorescence recovery aptasensor for sensitive detection of aflatoxin M(1) in milk.

Aflatoxin M1 (AFM1) contamination in milk and dairy products poses a significant food safety concern, highlighting the need for sensitive and reliable analytical methods. Herein, we developed a fluorescence recovery aptasensor that integrates hierarchical magnetic nano-orbs (HMO) as magnetic capture probes with aptamer-functionalized green-fluor...

#6 [11.1] Highly Sensitive Detection of Food Contaminants Based on an Efficient Quadrupedal DNA Walker

Abstract This research details the development of a highly efficient quadrupedal DNA walker designed for the detection of food contaminants. A cruciform DNA probe was synthesized through a straightforward methodology. Upon specific recognition between target analytes and aptamer sequences, the quadrupedal DNA walker is activated. This activation...

#7 [11.0] Electrospun nanofiber-based solid-phase extraction coupled with aptamer-mediated FRET assay for detection of aflatoxin M(1) in milk.

BACKGROUND: Aflatoxin M1 (AFM1), a highly toxic hydroxylated metabolite of aflatoxin B1, is a major contaminant of concern in milk and dairy products, posing significant risks to food safety and public health. Since AFM1 contamination is closely associated with feed quality, storage conditions, climatic factors, and farm management, reliable AFM...

#8 [10.8] A self-calibrating ratio fluorescence aptamer sensor based on PCN-224 for the highly sensitive detection of alternariol in cereals.

Alternariol (AOH) is an emerging mycotoxin widely found in agricultural products. It has drawn attention due to the potential health risks associated with long-term dietary exposure. Therefore, a ratiometric fluorescent aptamer sensor based on PCN-224 was developed. By combining the intrinsic fluorescence properties of PCN-224 with aptamer recog...

#9 [10.5] Machine learning-assisted broad-spectrum aptamer discovery and intelligent detection of neonicotinoid pesticides.

A machine learning-assisted computational strategy was developed for the de novo discovery of broad-spectrum aptamers targeting neonicotinoid pesticides (NEOs). Randomly generated DNA sequences were first classified according to secondary-structure similarity using t-distributed stochastic neighbor embedding (t-SNE) and K-means clustering, provi...

#10 [9.9] Streptavidin-Displaying E. coli Scaffolds Enable Target-Mediated Gold Nanoparticle Assembly for Colorimetric Biosensing

Enhancing the visual detection sensitivity of point-of-care (POC) optical sensors without resorting to complex, multistep chemical or enzymatic signal amplification remains a major challenge in sensor nanotechnology. Here, we present a multifunctional bio-nanostructured hybrid platform that integrates engineered Escherichia coli cellular scaffol...

Methodology