Aptamer 学术简报 — biosensor — 2026-10-17

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 77 篇命中（aptamer 池 141 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [23.5] Triple quenching strategy-based highly sensitive electrochemiluminescence sensor for perfluorooctanoic acid.

Quenching-based electrochemiluminescence (ECL) sensing boasts prominent advantages for trace analysis, while single-mechanism systems have inherent flaws, making the development of efficient synergistic quenching strategies of great practical significance for ultra-trace perfluorooctanoic acid (PFOA) detection. In this work, a zinc-coordinated p...

#2 [23.2] A dual-aptamer colorimetric sensor based on Cu-MOF@PtPdNPs for the highly sensitive detection of MUC1.

The abnormally high expression of MUC1 in various malignant tumors makes it a crucial biomarker for early cancer diagnosis. This study synthesized a Cu-MOF@PtPdNPs nanocomposite exhibiting robust peroxidase-like activity via an in-situ reduction method. By integrating this nanomaterial with a dual-aptamer recognition sandwich strategy, an effici...

#3 [14.6] Integrated Antigen–DNA Co‐Detection Using Digital Microfluidics for Improving Diagnostic Accuracy in POCT Analysis

ABSTRACT Simultaneous detection of protein and nucleic acid (NA) provides complementary information essential for accurate analysis of complex samples. Conventional approaches for the analysis of protein and NA typically rely on separate workflows and instruments, limiting the reliability of point‐of‐care testing. Here, we present a digital micr...

#4 [14.6] Integrated Antigen–DNA Co‐Detection Using Digital Microfluidics for Improving Diagnostic Accuracy in POCT Analysis

Simultaneous detection of protein and nucleic acid (NA) provides complementary information essential for accurate analysis of complex samples. Conventional approaches for the analysis of protein and NA typically rely on separate workflows and instruments, limiting the reliability of point-of-care testing. Here, we present a digital microfluidics...

#5 [14.1] Employment of mixed aptamers and gold nanobipyramids toward a paper-based aptasensor for simultaneously visual screening and accurate detection of eight sulfonamides.

A variety of sulfonamides (SAs) are extensively utilized in animal husbandry and aquaculture, necessitating the development of high-throughput methods for the rapid screening and accurate determination of multiple, ideally all commonly-applied SAs, in animal-derived foodstuffs. We herein developed a paper-based colorimetric aptasensor for the de...

#6 [13.1] Anchoring nanozymes on microneedles via nanotemplate sacrificial synthesis for glutathione detection.

Region-specific dysregulation of glutathione (GSH) reflects neuropsychiatric disorders and tumor progression. Microscale precision sampling combined with timely monitoring of GSH provides region-specific molecular information that may aid in disease diagnosis. To enable minimally invasive brain-compatible intraoperative detection of GSH within a...

#7 [13.1] Harigabri-Derived Carbon Dots as FRET Probes for E. coli Analysis.

Green-fluorescent carbon quantum dots (CQDs) were hydrothermally synthesized from the Mongolian medicine Harigabri, exhibiting uniform size (∼2.5 nm) and strong emission at 521 nm under 468 nm excitation. Based on the fluorescence resonance energy transfer (FRET) between the CQDs (donors) and AgNPs (acceptors), an aptamer-functionalized biosenso...

#8 [13.0] Repurposing Type III CRISPR-Cas as Modular Cellular RNA Biosensors

Abstract Over the past decade, CRISPR-Cas based biosensors have emerged as sensitive, specific and programmable platforms for nucleic acid detection, with applications ranging from diagnostic tools, environmental monitoring and various applications in fundamental research. The vast majority of these biosensors are currently limited to in vitro a...

#9 [13.0] Ultrasensitive and Specific Detection of Neutralization-Correlated Serum Antibodies Via Secondary Antibody−DNA Linker-Mediated Magnetic Bead−Based Proximity Extension Assay

Abstract Sensitive, accurate, and readily deployable detection of neutralizing antibody (NAb) titers is essential for evaluating vaccine efficacy and population-level immunity. Here, we report an Antibody-DNA Linker (AND Linker) comprising a fusion of Protein A/G, a G4S flexible peptide, and duck circovirus replication initiator protein (DCV). T...

#10 [13.0] An “Off−On” Room-Temperature Phosphorescence Aptasensor for Direct Acetylcholinesterase Detection

Abstract Most acetylcholinesterase (AChE) assays quantify catalytic activity, which does not necessarily reflect protein abundance. Herein, an “off−on” room-temperature phosphorescence (RTP) aptasensor (CDs@SiO2/PEG-Apt-Q1) based on Förster resonance energy transfer (FRET) was developed for direct AChE protein detection. An AChE-binding DNA apt...

Methodology