Aptamer 学术简报 — biosensor — 2026-10-09

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 122 篇命中（aptamer 池 206 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [21.7] Synergistic MIP-aptamer dual-recognition on silver-decorated sulfur-doped graphene quantum dots (S-GQDs@Ag) nanohybrids for ultra-sensitive impedimetric carcinoembryonic antigen detection.

The clinical utility of Carcinoembryonic Antigen (CEA) as a cornerstone biomarker for oncological monitoring is frequently hindered by the limitations of traditional immunoassays, including high costs, specialized storage requirements, and complex procedural workflows. To address these challenges, we report the development of a high-performance ...

#2 [19.3] An ultrasensitive colorimetric platform for tetracycline based on the aptamer tailoring strategy and synergistic signal amplification of Au@Ce MOF.

In this study, a rapid Au@Ce MOF-Apt functionalized three-dimensional (3D) paper platform was constructed for the detection of TC in milk. To obtain a high-affinity aptamer (Apt), based on truncation and base mutation, resulting in high-affinity G-rich sequence aptamer (Apt-M24) (27 nt, -10.4 kcal/mol). Subsequently, the Apt-M24 was efficiently ...

#3 [19.3] A bioelectrochemical aptamer sensor using vanadium-porphyrinic metal-organic framework for noninvasive hydrocortisone monitoring in sweat.

Hydrocortisone (HC) is a vital steroid hormone secreted by the adrenal cortex that regulates how the body responds to stress, the immune system and metabolism. The primary objective of this study is the fabrication of an electrochemical aptamer sensor founded on a vanadium-porphyrin metal-organic framework (V-PMOF) to detect HC. V2CTx MXene acts...

#4 [17.1] High-sensitivity simultaneous discrimination and detection of structurally similar adenosine phosphates via DNA aptamer conformational changes in α-hemolysin nanopore.

Adenosine phosphates (ATP, ADP, and AMP) play critical roles in cellular processes, yet their simultaneous detection remains challenging due to high structural similarity. To overcome this limitation, we developed a nanopore-aptamer sensing platform capable of tracking single-molecule binding dynamics in real time. This method leverages the spec...

#5 [17.1] Multiplexed electrochemical aptasensor on a nanoporous electrode: towards sensitive and anti-fouling detection of procaine, ATP and adenosine in biofluids.

This study presents a green and simple one-step electrochemical strategy for preparing nanoporous gold electrodes. The method involves anodizing the gold electrode by linear sweep voltammetry (LSV) in an aqueous solution of l-ascorbic acid (AA) and hydrochloric acid (HCl). The gold electrodes were etched in solution by hydrochloric acid to gener...

#6 [14.6] dsRADAR: Imaging and Detecting Cellular dsRNA by Repurposing RNA‐Binding Proteins

ABSTRACT Double‐stranded RNA (dsRNA) is recognized by cellular receptors as a sign of viral infection, triggering the innate immune response. Cellular dysregulation can also lead to accumulation of endogenously produced dsRNA that stimulates a viral‐like immune response. Additionally, dsRNA contamination in RNA therapeutics can lead to harmful s...

#7 [14.6] dsRADAR: Imaging and Detecting Cellular dsRNA by Repurposing RNA‐Binding Proteins

ABSTRACT Double‐stranded RNA (dsRNA) is recognized by cellular receptors as a sign of viral infection, triggering the innate immune response. Cellular dysregulation can also lead to accumulation of endogenously produced dsRNA that stimulates a viral‐like immune response. Additionally, dsRNA contamination in RNA therapeutics can lead to harmful s...

#8 [13.7] Ultrasensitive Electrochemiluminescence Aptasensor With DNA Nanotetrahedron Amplification for Multilevel Detection of cTnI From Cells to Patients.

Accurate detection of myocardial injury (MI) biomarkers for assessing anticancer drug-induced cardiotoxicity has long been constrained by insufficient capture efficiency and limited assay sensitivity. To address this challenge, we developed an electrochemiluminescence (ECL) aptasensor for the detection of cardiac troponin I (cTnI) based on a two...

#9 [13.5] CuCo alloy-embedded carbon nanocages for simultaneous biosensing of Hg(2+) and Cd(2+) in environmental water.

Mercury ions (Hg2+) and cadmium ions (Cd2+) are highly toxic heavy metals that can easily accumulate in the food chain and pose serious threats to the environment. However, achieving sensitive and efficient identification and determination of trace Hg2+ and Cd2+ remain a major challenge in real water environment. In this work, we developed an ul...

#10 [13.3] Double-Lock Superpolymer TDN is Used for the Theranostics of HCC

Abstract Hepatocellular carcinoma (HCC) is difficult to diagnose early and treat effectively due to its heterogeneity and lack of highly specific biomarkers. Here, we develop a double-lock superpolymer tetrahedral DNA (TDN) integrated with small extracellular vesicles (SUPDIA) for HCC theranostics. The TDN incorporates an HSP70 aptamer and a miR...

Methodology