Aptamer 学术简报 — biosensor — 2026-09-20

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 86 篇命中（aptamer 池 136 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [17.3] Selection and validation of novel DNA aptamer panel co-specific to Plasmodium falciparum and Plasmodium ovale lactate dehydrogenase.

Malaria remains a major global health concern. The development of point-of-care diagnostic aptasensors could improve malaria detection, patient management, and eradication efforts. We selected and validated single-stranded DNA aptamers against Plasmodium falciparum lactate dehydrogenase (Pf-LDH), using systematic evolution of ligands by exponent...

#2 [14.0] Rapid‐Forming Conductive Antifouling Hydrogel Coating Enables Magnetically Guided Electrochemical POCT for Direct at‑Home Blood Testing

ABSTRACT Electrochemical point‐of‐care testing for complex clinical samples is frequently hampered by matrix interference, signal instability, and laborious electrode modification procedures. Herein, we report a magnetic portable electrochemical immunosensor utilizing a conductive, anti‐fouling hydrogel coating composed of sodium alginate, polye...

#3 [13.8] Thermosensitive NIR-II fluorescence nanotracer for targeted detection of sentinel lymph nodes

Current tracers for sentinel lymph node (SLN) biopsy in breast cancer suffer from limitations including poor accumulation, short retention times, and background staining interference at the surgical site. To address these shortcomings, we developed a dual-functional thermoresponsive nanotracer based on PbS quantum dots functionalized with poly(N...

#4 [13.3] High‐Performance Optical Fiber SPR Biosensor for Label‐Free Detection of miRNA‐588 Toward Osteosarcoma Diagnosis

ABSTRACT Osteosarcoma is a malignant bone tumor for which diagnosis is critical to patient prognosis. MicroRNA‐588 is downregulated in osteosarcoma, highlighting its potential as a diagnostic biomarker. However, its low abundance in body fluids makes sensitive detection difficult. This study presents a label‐free reflective optical fiber surface...

#5 [13.3] RPA-CRISPR/Cas12a and Aptamer-Based Electrochemical Biosensing Duplex Platform for On-Site Monitoring of Antimicrobial Resistance in Water

Abstract Monitoring antimicrobial resistance (AMR) in aquatic systems is essential for tracking resistance mechanisms and identifying microbial sources. Here, we present a dual-module electrochemical sensing platform that integrates a gold-electrode-based RPA–CRISPR/Cas12a biosensor for detecting antibiotic resistance genes (ARGs) with a paper-b...

#6 [13.1] Highly specific aptamer-based structure-switching sensor for detection of the smallest alkali metal ion Li(+) in serum.

Lithium carbonate, a frontline drug for bipolar disorder (BD), requires strict therapeutic drug monitoring (TDM) due to its narrow therapeutic window (0.6-1.2 mM). Existing methods like inductively coupled plasma mass spectrometry (ICP-MS) and ion-selective electrodes (ISE) struggle to balance point-of-care testing (POCT) demands with interferen...

#7 [13.1] In situ monitoring of ferroptosis via dual-mode imaging of TFR1 expression using an aptamer-engineered MOF-Ag nanohybrid.

Ferroptosis is closely associated with the cytotoxicity of foodborne contaminants, with Transferrin Receptor 1 (TFR1) serving as a critical biomarker. Consequently, the in situ dynamic monitoring of TFR1 is crucial for unraveling the toxicological mechanisms underlying foodborne toxicity. To address the challenges of interference and insufficien...

#8 [13.0] An interface-regulated colorimetric-electrochemical dual-mode aptasensor for acetamiprid detection.

Matrix-derived electroactive interference remains a major analytical challenge for electrochemical aptasensors in complex food samples. We develop a sequential dual-mode aptasensor based on interface regulation for reliable colorimetric screening and electrochemical quantification of acetamiprid. The aptasensor is constructed on a g‑C₃N₄/AuNP-mo...

#9 [13.0] Freeze-thaw-directed interfacial assembly of a gold nanoparticle/MXene electrochemical aptamer sensor for antibody-free myeloperoxidase detection.

An electrochemical aptamer-based (E-AB) sensor for myeloperoxidase (MPO) was developed that combined a gold nanoparticle /MXene scaffold with freeze-thaw-directed aptamer immobilization and probe-density optimization. Unlike using nanocomposite amplification alone, this strategy regulates probe density and accessibility at the bioreceptor layer ...

#10 [13.0] Water-induced supramolecular self-assembly of porphyrin integrated with multivalent metal-organic framework for enhanced electrochemiluminescence and ultrasensitive aptasensing of 4-fluoromethamphetamine.

Aggregation-caused quenching (ACQ) and poor aqueous solubility severely restrict electrochemiluminescence (ECL) applications of polycyclic aromatic hydrocarbons (PAHs). Herein, a water-induced supramolecular self-assembly strategy is proposed to address these drawbacks. Via a simple reprecipitation route, representative PAH meso-tetrakis(4-carbo...

Methodology