Aptamer 学术简报 — biosensor — 2026-08-24

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 129 篇命中（aptamer 池 205 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [20.9] Bifunctional DNA multivalent structure integrating stable capture of urothelial carcinoma cells with CRISPR/Cas12a signal amplification for bladder cancer detection.

Noninvasive detection of bladder cancer remains challenging due to the limited analytical performance of current urine-based assays under realistic detection conditions. Here, we report a linear programmable DNA nanostructure that integrates multivalent aptamer recognition with CRISPR/Cas12a signal transduction for detecting tumor-derived urinar...

#2 [19.6] Shell-thickness-modulated electrochemiluminescence of colloidal quantum dots for ultrasensitive PSA detection.

Electrochemiluminescence (ECL) biosensors hold great promise for clinical diagnostics, yet their performance is often constrained by the limited efficiency and stability of available luminophores in complex biological matrices. Colloidal quantum dots (QDs) have emerged as attractive alternatives to conventional emitters, but a systematic underst...

#3 [17.4] Integrated single-tube detection of miRNAs in subpopulation-specific extracellular vesicles via spatially colocalized dual-module DNA scaffold.

Extracellular vesicles (EVs)-derived miRNAs are valuable non-invasive biomarkers for early cancer diagnosis. However, most current methods detect either total EVs-miRNAs or those from a single subpopulation, overlooking subpopulation heterogeneity. Moreover, EVs isolation and miRNA analysis are often conducted in separate workflows, increasing s...

#4 [16.4] Steric hindrance effect synergizing hole-trapping technique: High-Stability and high-accuracy Si/CdS n-n heterojunction photoelectrochemical biosensing of amyloid-β42.

Due to rapid carrier recombination and photodegradation, cadmium sulfide (CdS), an n-type semiconductor photosensitive material, has a low utilization efficiency that restricts its use in biosensing. A synergistic hole-trapping approach utilizing steric hindrance effects is proposed in this paper. First, chemical bath deposition (CBD) is used to...

#5 [14.9] Electropolymerized Aptasensor for Femtogram-Level Cytokine Detection.

Detecting cytokines at ultralow concentrations is important for the early diagnosis and monitoring of inflammatory and immune disorders, yet remains constrained by the sensitivity and stability of bioelectronic interfaces. Here, we present an electropolymerization strategy for preparing poly(amino-ʟ-tyrosine) (pALT) nanofilms as functional bioin...

#6 [14.8] Biomaterials Meet Organic Electrochemical Transistors: Materials, Interfaces, and Biosensing Frontiers

ABSTRACT Organic electrochemical transistors (OECTs) are emerging as powerful biosensing platforms, offering high transduction efficiency, low‐voltage operation, and intrinsic compatibility with aqueous and physiological environments. Central to their recent progress is the strategic integration of biomaterials, which govern interfacial charge t...

#7 [13.7] Plasmon‐Driven Gene Amplification‐Integrated Lateral Flow Assay for Ultrafast Diagnosis of Seoul Orthohantavirus

Accurate and rapid nucleic acid detection is vital for the early diagnosis of infectious diseases. Conventional polymerase chain reaction (PCR) offers high sensitivity but is hindered by bulky equipment, long processing times, and the need for technical expertise, limiting its point-of-care testing (POCT) applications. To overcome these constrai...

#8 [13.3] Near-Adjacent HeavyLanthanide Separation and SensingUsing Dimerizing Lanmodulins

Abstract Protein-based recovery, detection, and separation of rare earth elements (REs) have accelerated since the discovery of the lanmodulin (LanM) proteins. While exceptional at total RE recovery, prior proteins, like most ligands, exhibited limited ability to differentiate REs, whether in detection or separations. Here we report two dimerizi...

#9 [13.0] Resampling–Iteration–Evolution (RIE): A Rational Design System for Engineering High-Affinity Peptides against Small Molecules

Abstract Peptides are attractive molecular recognition elements because of their compact size, ease of modification, and structural tunability. The design of high-affinity peptides for small molecules lags far behind that of antibodies and aptamers due to the lack of general and effective discovery and optimization strategies. Computational desi...

#10 [13.0] Dual MOFs synergistically modulate electrode interface electron transfer to enhance electrochemiluminescence for ultrasensitive FB1 sensing.

Accurate detection of Fumonisin B1 (FB1) is of great significance for food safety and disease prevention and control. In this work, the construction of dual metal-organic frameworks (MOFs) synergistically modulated electron transfer at the electrode interface, thereby enhancing ECL emission. This approach enabled ultrasensitive detection of fumo...

Methodology