Aptamer 学术简报 — biosensor — 2026-08-13

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 123 篇命中（aptamer 池 200 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [16.6] AptaStick: A 3D-printed aptamer-functionalized stir-stick for selective extraction of bisphenol A from soft drinks.

This work presents AptaStick, a stereolithography 3D-printed stir-stick device functionalized with a bisphenol A (BPA)-specific aptamer for selective extraction from soft drinks. For this purpose, several geometries were evaluated to optimize extraction performance, with a star-shaped design providing the highest extraction efficiency and reprod...

#2 [15.9] A PD-L1-targeted and lactate-responsive DNA hydrogel enabling Mito-US therapy: dual functions for postsurgical cancer detection and eradication.

The minimal residual disease (MRD) following tumor resection remains a major challenge for preventing recurrence. Existing treatments usually exhibit poor specificity for scattered tumor cells at the surgical site. Moreover, few strategies successfully combine real-time MRD monitoring with sustained therapeutic intervention, further limiting the...

#3 [15.6] Multiplexed nanophotonic sensor arrays for time-resolved biomolecular analysis.

Complex diseases arise from networks of interacting biomolecules, yet most analytical technologies measure only a limited number of interactions simultaneously. Here, we present a chirped guided-mode resonance (cGMR) photonic biosensor array for multiplexed, label-free analysis of biomolecular kinetics across hundreds of sensing sites. The platf...

#4 [14.9] Harnessing Synergistic Enthalpy‐Entropy Regulation: An I‐Motif‐Based Modulating Design for Programming Stimulus‐Responsive DNA Switches

ABSTRACT DNA switches with target‐induced allostery show great potential in biomedical application, yet often remain unprogrammable responses and limited accuracy. Existing designs also lack adaptability beyond predefined response windows and offer limited sensitivity tuning. Herein, we present an i‐motif‐based modulating design that leverages e...

#5 [14.9] Harnessing Synergistic Enthalpy-Entropy Regulation: An I-Motif-Based Modulating Design for Programming Stimulus-Responsive DNA Switches.

DNA switches with target-induced allostery show great potential in biomedical application, yet often remain unprogrammable responses and limited accuracy. Existing designs also lack adaptability beyond predefined response windows and offer limited sensitivity tuning. Herein, we present an i-motif-based modulating design that leverages enthalpy-e...

#6 [14.8] Aptamer-cDNA-driven nanozyme strategy: A recyclable dual-signal immunosensor for amplified detection of aflatoxin B(1) in edible oil.

Aflatoxin B1 (AFB1) poses a serious threat to human health, highlighting theurgent need for sensitive, precise and visual detection methods in daily foods. However,traditional detection methods relying on peroxidase (POD)-mimetic activity are susceptible to external interference, which increases false-positive or false-negative rates and comprom...

#7 [14.6] Aptamer-integrated DNA tetrahedral sensors for cancer cell imaging and invasiveness assessment.

DNA tetrahedron is a nanoscale framework self-assembled from DNA strands. Their nucleic acid composition confers excellent biocompatibility, rendering them highly suitable for drug delivery and biomarker imaging applications. Aptamers are short oligonucleotides that bind target proteins with high affinity and specificity. Integration of multiple...

#8 [14.1] Fabrication of electrochemical biosensor with a CD36 aptamer and AuMoS(2) heterolayer for tumor-derived exosome detection.

Breast cancer (BC), which is often diagnosed at advanced stages owing to its asymptomatic progression, presents with substantial molecular heterogeneity, leading to diverse therapeutic responses and prognostic outcomes. Among its molecular subtypes, the human epidermal growth factor receptor 2-positive/hormone receptor-negative (HER2+/HR-) pheno...

#9 [13.5] Photoelectrochemical and colorimetric dual-mode aptasensor for nonylphenol detection in food based on ascorbic acid-sensitive Bi(2)S(3)/Bi(2)O(2)CO(3) heterojunction and multi-enzyme-mimicking Ce-MOF.

A simple and novel photoelectrochemical (PEC)-colorimetric (CL) dual-mode aptasensor was explored for nonylphenol determination using ascorbic acid (AA)-sensitive Bi2S3/Bi2O2CO3Z-Scheme heterojunction and Ce(III/IV)-MOF (R-UiO66-Ce) with dual enzyme-mimetic activity. Firstly, ascorbic acid phosphate was hydrolyzed under R-UiO66-Ce catalysis to g...

#10 [13.3] DNA-Functionalized Covalent Organic Framework for Colorimetric Detection and Adsorption Removal of Uranyl Ions.

Inspired by the modulatable nanozymatic activity of covalent organic frameworks (COFs) by single-stranded DNA (ssDNA), herein, we developed a versatile platform for sensitive/specific colorimetric detection and efficient adsorption of UO22+ based on DNA aptamer-functionalized COFs. Three COFs with varying alkyne contents (Py-BDA, Py-BDA-BPTA, an...

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