Aptamer 学术简报 — biosensor — 2026-08-05

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 98 篇命中（aptamer 池 174 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [23.0] AptaStick: A 3D-printed aptamer-functionalized stir-stick for selective extraction of bisphenol A from soft drinks.

This work presents AptaStick, a stereolithography 3D-printed stir-stick device functionalized with a bisphenol A (BPA)-specific aptamer for selective extraction from soft drinks. For this purpose, several geometries were evaluated to optimize extraction performance, with a star-shaped design providing the highest extraction efficiency and reprod...

#2 [21.9] A PD-L1-targeted and lactate-responsive DNA hydrogel enabling Mito-US therapy: dual functions for postsurgical cancer detection and eradication.

The minimal residual disease (MRD) following tumor resection remains a major challenge for preventing recurrence. Existing treatments usually exhibit poor specificity for scattered tumor cells at the surgical site. Moreover, few strategies successfully combine real-time MRD monitoring with sustained therapeutic intervention, further limiting the...

#3 [20.9] Aptamer-cDNA-driven nanozyme strategy: A recyclable dual-signal immunosensor for amplified detection of aflatoxin B(1) in edible oil.

Aflatoxin B1 (AFB1) poses a serious threat to human health, highlighting theurgent need for sensitive, precise and visual detection methods in daily foods. However,traditional detection methods relying on peroxidase (POD)-mimetic activity are susceptible to external interference, which increases false-positive or false-negative rates and comprom...

#4 [20.7] Fabrication of electrochemical biosensor with a CD36 aptamer and AuMoS(2) heterolayer for tumor-derived exosome detection.

Breast cancer (BC), which is often diagnosed at advanced stages owing to its asymptomatic progression, presents with substantial molecular heterogeneity, leading to diverse therapeutic responses and prognostic outcomes. Among its molecular subtypes, the human epidermal growth factor receptor 2-positive/hormone receptor-negative (HER2+/HR-) pheno...

#5 [20.6] Aptamer-integrated DNA tetrahedral sensors for cancer cell imaging and invasiveness assessment.

DNA tetrahedron is a nanoscale framework self-assembled from DNA strands. Their nucleic acid composition confers excellent biocompatibility, rendering them highly suitable for drug delivery and biomarker imaging applications. Aptamers are short oligonucleotides that bind target proteins with high affinity and specificity. Integration of multiple...

#6 [19.2] Surface activation and functionalization with aryl-diazonium chemistry enable biomolecules grafting on 3D printed carbon-based electrodes.

Carbon-based electrodes printed using fused deposition modelling (FDM) technology constitute appealing platforms for electrochemical biosensors. However, immobilizing bioreceptors that retain their stability and recognition properties at the electrode surface is quite challenging. So far, only few successful biosensors based on covalently bindin...

#7 [16.8] A novel label-free electrochemical aptamer sensor based on base mismatch and strand displacement for detection of kanamycin.

Misuse of kanamycin in animal husbandry has led to serious food safety issues. In this study, a label-free electrochemical aptasensor based on the base mismatch and strand displacement was developed for detection of kanamycin residue in agricultural products. A novel ferrocene-naphthalimide derivative was employed as the electroactive indicator....

#8 [13.7] Lock-Open: An AND Logic-Gated, Entropy-Driven DNA Nanowalker for Highly Sensitive Detection of UDG and APE1 Activities in Hepatocellular Carcinoma.

Early diagnosis of HCC remains a clinical challenge, with survival strongly dependent on reliable biomarkers and translatable detection tools. Herein, we establish uracil-DNA glycosylase (UDG) and apurinic/apyrimidinic endonuclease 1 (APE1) as diagnostic biomarkers for early-stage HCC and develop a lock-open strategy based on an AND logic-gated,...

#9 [13.5] Multiplexed nanophotonic sensor arrays for time-resolved biomolecular analysis.

Complex diseases arise from networks of interacting biomolecules, yet most analytical technologies measure only a limited number of interactions simultaneously. Here, we present a chirped guided-mode resonance (cGMR) photonic biosensor array for multiplexed, label-free analysis of biomolecular kinetics across hundreds of sensing sites. The platf...

#10 [13.5] Fluctuation-resilient ratiometric SERS enabled by programmable aptamer disassembly for pump-free microfluidic AKI detection.

Acute kidney injury (AKI) requires rapid and reliable biomarker quantification, yet early assessment is hindered by delayed biomarker kinetics and signal fluctuation under decentralized testing conditions. Here, we developed a pump-free microfluidic aptamer-ratiometric surface-enhanced Raman scattering (SERS) platform for simultaneous quantifica...

Methodology