Aptamer 学术简报 — biosensor — 2026-08-01

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 111 篇命中（aptamer 池 183 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [15.6] Inception-level signal amplification: Cascaded DNAzyme-Cas9 nickase achieves sub-nanomolar kanamycin tracking.

BACKGROUND: Kanamycin's persistent contamination in agricultural products poses significant human health risks due to its nephrotoxicity and bioaccumulation via the food chain. Existing methods for on-site kanamycin monitoring lack sufficient sensitivity and portability, limiting their utility in field settings. The urgent need for rapid detecti...

#2 [15.6] The integration of peptoid and phosphorothioate aptamer into electrochemical biosensors for the robust antifouling detection of prostate-specific antigen in human serum.

Electrochemical biosensors for biomarker detection in complex biological media often suffer from performance degradation. Two main causes are non-specific adsorption of biomolecules and enzymolysis of immobilized biomolecules. Consequently, the development of robust antifouling electrochemical biosensors represents an imperative research task. W...

#3 [15.1] A PD-L1-targeted and lactate-responsive DNA hydrogel enabling Mito-US therapy: dual functions for postsurgical cancer detection and eradication.

The minimal residual disease (MRD) following tumor resection remains a major challenge for preventing recurrence. Existing treatments usually exhibit poor specificity for scattered tumor cells at the surgical site. Moreover, few strategies successfully combine real-time MRD monitoring with sustained therapeutic intervention, further limiting the...

#4 [14.8] Multiplexed nanophotonic sensor arrays for time-resolved biomolecular analysis.

Complex diseases arise from networks of interacting biomolecules, yet most analytical technologies measure only a limited number of interactions simultaneously. Here, we present a chirped guided-mode resonance (cGMR) photonic biosensor array for multiplexed, label-free analysis of biomolecular kinetics across hundreds of sensing sites. The platf...

#5 [14.8] Fluctuation-resilient ratiometric SERS enabled by programmable aptamer disassembly for pump-free microfluidic AKI detection.

Acute kidney injury (AKI) requires rapid and reliable biomarker quantification, yet early assessment is hindered by delayed biomarker kinetics and signal fluctuation under decentralized testing conditions. Here, we developed a pump-free microfluidic aptamer-ratiometric surface-enhanced Raman scattering (SERS) platform for simultaneous quantifica...

#6 [14.1] Aptamer-cDNA-driven nanozyme strategy: A recyclable dual-signal immunosensor for amplified detection of aflatoxin B(1) in edible oil.

Aflatoxin B1 (AFB1) poses a serious threat to human health, highlighting theurgent need for sensitive, precise and visual detection methods in daily foods. However,traditional detection methods relying on peroxidase (POD)-mimetic activity are susceptible to external interference, which increases false-positive or false-negative rates and comprom...

#7 [13.8] Aptamer-integrated DNA tetrahedral sensors for cancer cell imaging and invasiveness assessment.

DNA tetrahedron is a nanoscale framework self-assembled from DNA strands. Their nucleic acid composition confers excellent biocompatibility, rendering them highly suitable for drug delivery and biomarker imaging applications. Aptamers are short oligonucleotides that bind target proteins with high affinity and specificity. Integration of multiple...

#8 [13.8] A DNA tetrahedral nanostructure actuates a "signal-off" fluorescent biosensor for ultrasensitive detection of mercury ions.

The performance of fluorescent Hg2+ biosensors is fundamentally limited by the high background noise inherent in conventional "signal-on" designs. Here, we overcome this limitation by engineering a "signal-off" nanosensor based on a programmable tetrahedral DNA nanostructure (TDN). This scaffold is precisely functionalized with vertex quenchers ...

#9 [13.8] AptaStick: A 3D-printed aptamer-functionalized stir-stick for selective extraction of bisphenol A from soft drinks.

This work presents AptaStick, a stereolithography 3D-printed stir-stick device functionalized with a bisphenol A (BPA)-specific aptamer for selective extraction from soft drinks. For this purpose, several geometries were evaluated to optimize extraction performance, with a star-shaped design providing the highest extraction efficiency and reprod...

#10 [13.8] Cysteine exerts surface polarization effect on BiOCOOH for photoelectrochemical detection of small molecules.

The exploration of new kinds of materials with novel sensing mechanisms for photoelectrochemical (PEC) analysis are crucial for advancing efficient PEC detection. This study demonstrated that cysteine (Cys) induced surface polarization effect (SPE) on the surface of the environmentally friendly layered bismuth-based semiconductor material, i.e.,...

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