Aptamer 学术简报 — biosensor — 2026-07-31

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 95 篇命中（aptamer 池 165 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [16.2] Inception-level signal amplification: Cascaded DNAzyme-Cas9 nickase achieves sub-nanomolar kanamycin tracking.

BACKGROUND: Kanamycin's persistent contamination in agricultural products poses significant human health risks due to its nephrotoxicity and bioaccumulation via the food chain. Existing methods for on-site kanamycin monitoring lack sufficient sensitivity and portability, limiting their utility in field settings. The urgent need for rapid detecti...

#2 [16.2] The integration of peptoid and phosphorothioate aptamer into electrochemical biosensors for the robust antifouling detection of prostate-specific antigen in human serum.

Electrochemical biosensors for biomarker detection in complex biological media often suffer from performance degradation. Two main causes are non-specific adsorption of biomolecules and enzymolysis of immobilized biomolecules. Consequently, the development of robust antifouling electrochemical biosensors represents an imperative research task. W...

#3 [13.2] Detection of Point Mutation in Individual Living Circulating Malignant Cells by Targeting Molecular Beacon Delivery.

As a prevalent form of genetic alteration, single-base substitution serves as a critical determinant of targeted cancer therapeutic strategies and a driver of acquired drug resistance. Despite its clinical significance, detecting these mutations at the single-cell level remains challenging due to high costs, long analysis times, and difficulties...

#4 [12.7] An Electro-Fenton-Driven Self-Ratio Electrochemiluminescence Sensing Platform without a Coreactant for Sensitive and Accurate Monitoring of Antibiotics.

A ratiometric electrochemiluminescence (ECL) sensor with a self-calibration function can significantly enhance the detection accuracy of analytes. However, the requirement for two suitable ECL emitters and their corresponding coreactants often limits its practical applicability. In this study, luminol was employed as a single ECL emitter combine...

#5 [12.6] Steric-gated nanochannel biosensor for amplification-free electrochemical quantification of microbial DNA and RNA in aquatic environments

#6 [12.6] Light-addressable potentiometric sensors: principles, strategies, and applications.

Light-addressable potentiometric sensors (LAPS) provide a promising strategy for quantitative and spatially resolved detection of chemical biomarkers and electrophysiological signals in biological tissues. This review describes the working principles of LAPS, discusses key design considerations, and summarizes recent progress from the perspectiv...

#7 [12.5] Nano-enabled fluorescent sensing platforms for on-site detection of pesticides in food

: Pesticide residues in food matrices pose significant threats to global food safety. Conventional chromatographic methods, though highly reliable, are constrained by high costs, lengthy analysis times, and limited field deployability, restricting their use for rapid on-site monitoring across food supply chains. Nanomaterial-based fluorescent se...

#8 [12.5] Interfacially programmable triblock DNA probes enable highly specific PDGF-BB detection via proximity hybridization-induced strand displacement.

Selective detection of multimeric protein biomarkers is important for biomarker-related research and complex sample analysis; however, the performance of current sensing systems is often limited by insufficient control over the spatial organization of recognition probes at solid-phase interfaces. Herein, using platelet-derived growth factor-BB (...

#9 [12.5] Integration of dual-output TMSD and CRISPR/Cas12a for crosstalk-free electrochemiluminescence detection of aflD gene and AFB1.

Aflatoxins are among the most toxic mycotoxins and pose a severe threat to food safety and human health. In addition to the direct monitoring of aflatoxin B1 (AFB1), simultaneous detection of its key biosynthesis gene, aflD, can effectively indicate the presence of toxin-producing strains, thereby enhancing the early screening and traceability o...

#10 [12.3] Ultrasensitive Detection of Tumor-Derived Extracellular Vesicle microRNAs via Aptamer-Driven Targeted Membrane Fusion and Nonenzymatic Amplification.

Extracellular vesicles (EVs) have emerged as a prominent and rapidly evolving class of biomarkers, garnering an increasing amount of attention in recent years. The analysis of diverse EV-derived biomolecules, including proteins, mRNA, and miRNA, has driven the development of numerous innovative analytical technologies for EV detection. Neverthel...

Methodology