Aptamer 学术简报 — biosensor — 2026-07-01

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 145 篇命中（aptamer 池 244 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [27.2] AI-driven Cu/Mn-CeO(2) nanozyme-functionalized paper-based biosensor for quantitative monitoring of alternariol in food.

The lack of rapid, user-friendly methods for alternariol (AOH), a prevalent emerging mycotoxin, presents a considerable analytical challenge. This work introduces an integrated sensing strategy advancing from classical homogeneous liquid-phase detection to a portable AI-enhanced paper-based biosensor. The system employed a Cu/Mn-CeO2 nanozyme as...

#2 [18.4] A photocurrent polarity switching photoelectrochemical aptasensor based on Er-MOF nanosheets and methylene blue for high-performance determination of CA15-3.

BACKGROUND: Photoelectrochemical (PEC) biosensors have attracted increasing interest for tumor biomarker detection due to their intrinsic advantages. However, conventional PEC sensing strategies are typically based on unidirectional "signal-on" or "signal-off" modes, which are vulnerable to matrix interferences in complex biological samples and ...

#3 [14.8] Magnetically induced aggregation-assisted mesoporous polydopamine/single-atom nanozyme platform for dual-channel detection and two-stage synergistic eradication of pathogens.

Contamination with foodborne pathogenic bacteria poses a severe threat to public health, necessitating the integration of detection with source sterilization technologies. Herein, we developed an integrated nanoplatform by combining an aptamer-modified mesoporous polydopamine/palladium single-atom carbon dot composite probe (MPDA/Pd SA@DA-CDs/Ap...

#4 [14.8] High affinity and selective DNA aptamers for the detection of tobramycin in eye drops.

Tobramycin is a frontline aminoglycoside antibiotic with a narrow therapeutic window. Here, we report the selection of high-affinity DNA aptamers using a library-immobilization based SELEX strategy. The lead aptamer, TOB-2, binds tobramycin with a dissociation constant of 420 nM as determined by isothermal titration calorimetry, while exhibiting...

#5 [14.8] Nanoconfined biosensor for attomolar molecule detection and recycling via DNA strand displacement.

Attomolar-level biomolecular detection remains challenging due to inefficient molecular collisions and weak signal transduction at ultralow concentrations. Here, we introduce a recyclable nanoconfined biosensing platform (ABA@NCBS) for adenosine triphosphate (ATP) detection. This platform integrates a programmable DNA strand displacement reactio...

#6 [14.1] Synergistic graphene-aptamer coating on a flexible metasurface enables on-apple terahertz sensing of pesticides.

The critical need for rapid, on-site pesticide detection has driven interest in terahertz (THz) sensing. This study presents a flexible THz metasurface functionalized with an aptamer-graphene hybrid layer for specific detection of chlorpyrifos. Graphene enriches target molecules via π-π stacking, while the aptamer ensures precise recognition. Us...

#7 [14.0] A Self-Powered Sensing Platform Based on the Janus Heterostructure for Machine Learning-Assisted Dual-Mode Detection of 17β-Estradiol.

Interfacial energy level mismatch and inefficient charge extraction at bioelectrochemical interfaces have remained major bottlenecks for enzymatic biofuel cell-based self-powered sensing systems. Here, we reported a built-in electric field (BIEF) enabled self-powered sensing platform for intelligent dual-mode detection of 17β-estradiol (E2), fea...

#8 [13.8] Extended-gate FET biosensor utilizing ionic strength engineering for sensitive prostate-specific antigen detection.

This work presents an extended-gate field-effect transistor (EGFET) biosensor functionalized with prostate-specific antigen (PSA) aptamers. It employs ionic strength engineering to enhance electrostatic coupling and improve detection sensitivity. By systematically adjusting the concentration of phosphate-buffered saline (PBS), we modified the el...

#9 [13.8] Microscale thermophoresis sensor for homogeneous and one-step protein detection based on dual aptamers binding induced DNA switch.

Rapid and sensitive detection of proteins is in great demand in disease diagnostics, drug discovery, basic research, and other biomedical applications. The emerging microscale thermophoresis (MST) technique, which enables to monitor fluorescence responses of fluorescent molecules under heating in real time, provides an attractive avenue for sens...

#10 [13.8] Biofilm surface proximity-induced branched hybridization chain reaction strategy based on microchip electrophoresis for distinguishing exosomes from different cancer cells.

The exosome surface contains various cancer markers that can be suitable candidates for early cancer diagnosis and therapeutic efficacy evaluation. However, due to the very small size of exosomes, major challenges remain to detect tumor markers on their surface. To circumvent these challenges, a signal amplification strategy based on microchip e...

Methodology