Aptamer 学术简报 — biosensor — 2026-06-22

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 86 篇命中（aptamer 池 168 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [18.8] Dual-readout aptasensor based on CRISPR/Cas12a and nanozyme for accurate detection of KIM-1 and its application in kidney transplant prognosis.

Kidney injury molecule-1 (KIM-1) has emerged as a pivotal prognostic biomarker for renal allograft function. However, its detection remains challenging due to sensitivity and accuracy limitations. An innovative biosensing platform synergizing aptamer recognition, CRISPR trans-cleavage and nanozyme amplification for dual-readout KIM-1 detection h...

#2 [16.6] Aptamer modified NPA hollow nanozymes with intrinsic peroxidase-like activity for colorimetric sensing of H1N1.

A colorimetric sensor based on aptamer-functionalized nanozyme probes was successfully developed for the sensitive and specific detection of influenza A (H1N1) virus. In this study, trimetallic nickel-palladium-gold hollow nanozymes (NPA) with excellent peroxidase (POD)-like activity were used as catalytic probes. Compared to the horseradish per...

#3 [14.2] Target-Specific Recognition and Standardized Readout: A DNA Nanotransduction Strategy for Nanopore Exosome Sensing toward Clinical Applications.

Solid-state nanopores are powerful single-molecule sensing tools, but their reliance on direct translocation requires high analyte concentrations and complicates biochemical specificity. We propose a DNA nanotransduction strategy featuring target-specific molecular recognition and standardized electrical readout, converting complex vesicular inf...

#4 [14.1] NHAPL enables homogeneous detection of RNA-associated glycan signals.

GlycoRNAs, newly identified RNA molecules bearing glycan modifications on cell membranes, are implicated in cell communication and immune regulation. However, current methodological limitations impede a thorough elucidation of their biological roles and clinical significance. Here, we developed Nucleotides Hybridization and Aptamer-based Proximi...

#5 [13.8] Functionalized carbon nanotube-assisted dual-mode CRISPR/Cas12a detection of hepatitis C virus via catalytic assembly circuit-driven Y-shaped dsDNA activators.

Hepatitis C virus (HCV) is a major etiological agent of liver diseases and remains a serious global health threat. Herein, we report a dual-modal HCV biosensing platform for ultrasensitive HCV RNA detection by integrating near-infrared fluorescence and colorimetric readouts. In this system, the presence of HCV RNA initiates a catalytic assembly ...

#6 [13.6] Ultrasensitive dual-detection of antibiotics in animal-derived foods by nucleic acid signal amplification-assisted magnetic dispersive solid-phase extraction.

BACKGROUND: The presence of diverse residual trace antibiotics in various food matrices may accumulate in the human body through the food chain and potentially pose a significant risk to human health through synergistic effects. Consequently, the development of a sensitive method for the simultaneous detection of multiple antibiotics holds signi...

#7 [13.6] A photocurrent polarity switching photoelectrochemical aptasensor based on Er-MOF nanosheets and methylene blue for high-performance determination of CA15-3.

BACKGROUND: Photoelectrochemical (PEC) biosensors have attracted increasing interest for tumor biomarker detection due to their intrinsic advantages. However, conventional PEC sensing strategies are typically based on unidirectional "signal-on" or "signal-off" modes, which are vulnerable to matrix interferences in complex biological samples and ...

#8 [13.3] An Engineered Core-Satellite Magnetic Aptasensor with Built-In Calibration and Regeneration for Accurate Quantification of Oral Cancer Exosomes.

Exosomes carry diverse biologically active substances that can be transferred between cells, thereby influencing physiological and pathological states of the organism. Abnormal exosome levels are closely associated with cancer. Consequently, the precise detection of exosomes holds considerable importance for noninvasive cancer diagnosis and moni...

#9 [13.0] Real-Time Monitoring of Trastuzumab Monoclonal Antibodies Using Electrochemical Aptamer-Based Sensors.

The real-time monitoring of trastuzumab (Tmab), a monoclonal antibody used for cancer treatment, is critical for personalized, response-guided dosing and improved biomanufacturing quality control. Currently, Tmab concentrations are quantified using immunoassays and mass spectrometry, but these platforms provide only discrete measurements and req...

#10 [13.0] Aptamer-functionalized 2D photonic crystal hydrogels for sensitive and selective Hg(2+) detection.

A two-dimensional photonic crystal hydrogel (2DPCH) sensor functionalized with aptamers has been developed for the highly sensitive detection of Hg2+ in water. The sensing mechanism relies on the specific formation of T- Hg2+-T hairpin structures between Hg2+ and the aptamers, inducing hydrogel contraction and altering the spacing between embedd...

Methodology