Aptamer 学术简报 — biosensor — 2026-06-18

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 68 篇命中（aptamer 池 155 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [22.9] Dual-readout aptasensor based on CRISPR/Cas12a and nanozyme for accurate detection of KIM-1 and its application in kidney transplant prognosis.

Kidney injury molecule-1 (KIM-1) has emerged as a pivotal prognostic biomarker for renal allograft function. However, its detection remains challenging due to sensitivity and accuracy limitations. An innovative biosensing platform synergizing aptamer recognition, CRISPR trans-cleavage and nanozyme amplification for dual-readout KIM-1 detection h...

#2 [19.0] Aptamer modified NPA hollow nanozymes with intrinsic peroxidase-like activity for colorimetric sensing of H1N1.

A colorimetric sensor based on aptamer-functionalized nanozyme probes was successfully developed for the sensitive and specific detection of influenza A (H1N1) virus. In this study, trimetallic nickel-palladium-gold hollow nanozymes (NPA) with excellent peroxidase (POD)-like activity were used as catalytic probes. Compared to the horseradish per...

#3 [14.3] Aptamer-functionalized 2D photonic crystal hydrogels for sensitive and selective Hg(2+) detection.

A two-dimensional photonic crystal hydrogel (2DPCH) sensor functionalized with aptamers has been developed for the highly sensitive detection of Hg2+ in water. The sensing mechanism relies on the specific formation of T- Hg2+-T hairpin structures between Hg2+ and the aptamers, inducing hydrogel contraction and altering the spacing between embedd...

#4 [14.3] Luminescent hydrogel-enabled electrochemiluminescent aptasensor and portable analyzer for on-site quantification of acetamiprid in vegetables.

Acetamiprid residues in vegetables threaten human health and food safety, necessitating rapid, sensitive detection. Electrochemiluminescence (ECL) is highly sensitive but suffers from matrix-induced quenching and high-voltage photomultiplier tubes (PMT). Here we co-load N-(4-aminobutyl)-N-ethylisoluminol (ABEI), MnO2 nanosheets (MnO2NSs), and go...

#5 [13.7] Reagent-Free Molecular Pendulum Biosensor with Antibody-Aptamer Dual Recognition for Protein Analysis.

The development of reagent-free biosensors that can continuously monitor proteins in complex biological fluids is still a critical unmet need. Molecular pendulum sensors have recently emerged as a promising reagent-free platform, enabling direct biomolecule detection without interference from surrounding matrices. However, conventional molecular...

#6 [13.5] A supersandwich fluorescent aptasensor leveraging the synergy of mini-nanotetrahedron, high-affinity split aptamer and rolling circle amplification for kanamycin analysis in milk.

Sensitive detection of kanamycin (KAN) is vital for ensuring food safety. In this study, a novel fluorescent aptasensor for KAN detection was developed by synergizing high-affinity split aptamers, a miniaturized DNA nanotetrahedron (mini-NTH) scaffold, and rolling circle amplification (RCA). Contrasting conventional views, the split aptamers exh...

#7 [13.3] Construction of Codirectional Charge Transfer Channels in Imine-Linked Covalent Organic Frameworks with Enhanced Electrochemiluminescence for Ultrasensitive Lincomycin Assay.

Covalent organic frameworks (COFs) have garnered increasing attention in electrochemiluminescence (ECL), but how to improve ECL efficiency is still challenging due to the insufficient charge separation driving forces and non-directional charge transfer. Herein, by rationally modulating the types of building blocks, we synthesize two donor-accept...

#8 [13.3] Streamlined Dual-Readout HPV-16 DNA Sensor Empowered by the Intrinsic Colorimetric and Electrochemiluminescent Activities of Nanocrystalline PCN-224

Metal–organic frameworks (MOFs) combine the merits of programmable porosity with versatile metal nodes/organic ligands, allowing the precise integration of specific recognition and signal transduction within a single crystalline cell. Thus, they serve as an optimal platform for developing integrated, multifunctional sensing probes. Studies frequ...

#9 [13.0] An Aptamer-Engineered Phenotyping System for Extracellular Vesicles Based on Honeycomb-like Melamine-Formaldehyde Microspheres and Carbon Dot Nanozymes.

Molecular phenotyping of extracellular vesicles (EVs) holds promise for noninvasive cancer diagnosis; however, current methodologies encounter limitations in cost, throughput, and sensitivity. Herein, we developed an aptamer-engineered phenotyping system designed for multiplexed, cost-effective, and user-friendly detection of EV membrane protein...

#10 [13.0] Double-layer core-satellite magnetic SERS aptasensor for ultrasensitive and interference-free tryptamine detection.

Excessive tryptamine in food poses a significant risk to human health, emphasizing the demand for efficient, sensitive, and rapid detection technologies. Surface-enhanced Raman Spectroscopy (SERS) aptasensors are presently attracting a lot of attention due to their ability to detect targets at low concentrations. However, their inherent instabil...

Methodology