Aptamer 学术简报 — biosensor — 2026-06-16

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 74 篇命中（aptamer 池 155 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [27.5] Dual-readout aptasensor based on CRISPR/Cas12a and nanozyme for accurate detection of KIM-1 and its application in kidney transplant prognosis.

Kidney injury molecule-1 (KIM-1) has emerged as a pivotal prognostic biomarker for renal allograft function. However, its detection remains challenging due to sensitivity and accuracy limitations. An innovative biosensing platform synergizing aptamer recognition, CRISPR trans-cleavage and nanozyme amplification for dual-readout KIM-1 detection h...

#2 [20.5] Aptamer modified NPA hollow nanozymes with intrinsic peroxidase-like activity for colorimetric sensing of H1N1.

A colorimetric sensor based on aptamer-functionalized nanozyme probes was successfully developed for the sensitive and specific detection of influenza A (H1N1) virus. In this study, trimetallic nickel-palladium-gold hollow nanozymes (NPA) with excellent peroxidase (POD)-like activity were used as catalytic probes. Compared to the horseradish per...

#3 [15.0] Aptamer-functionalized 2D photonic crystal hydrogels for sensitive and selective Hg(2+) detection.

A two-dimensional photonic crystal hydrogel (2DPCH) sensor functionalized with aptamers has been developed for the highly sensitive detection of Hg2+ in water. The sensing mechanism relies on the specific formation of T- Hg2+-T hairpin structures between Hg2+ and the aptamers, inducing hydrogel contraction and altering the spacing between embedd...

#4 [15.0] Luminescent hydrogel-enabled electrochemiluminescent aptasensor and portable analyzer for on-site quantification of acetamiprid in vegetables.

Acetamiprid residues in vegetables threaten human health and food safety, necessitating rapid, sensitive detection. Electrochemiluminescence (ECL) is highly sensitive but suffers from matrix-induced quenching and high-voltage photomultiplier tubes (PMT). Here we co-load N-(4-aminobutyl)-N-ethylisoluminol (ABEI), MnO2 nanosheets (MnO2NSs), and go...

#5 [14.1] A supersandwich fluorescent aptasensor leveraging the synergy of mini-nanotetrahedron, high-affinity split aptamer and rolling circle amplification for kanamycin analysis in milk.

Sensitive detection of kanamycin (KAN) is vital for ensuring food safety. In this study, a novel fluorescent aptasensor for KAN detection was developed by synergizing high-affinity split aptamers, a miniaturized DNA nanotetrahedron (mini-NTH) scaffold, and rolling circle amplification (RCA). Contrasting conventional views, the split aptamers exh...

#6 [14.0] Construction of Codirectional Charge Transfer Channels in Imine-Linked Covalent Organic Frameworks with Enhanced Electrochemiluminescence for Ultrasensitive Lincomycin Assay.

Covalent organic frameworks (COFs) have garnered increasing attention in electrochemiluminescence (ECL), but how to improve ECL efficiency is still challenging due to the insufficient charge separation driving forces and non-directional charge transfer. Herein, by rationally modulating the types of building blocks, we synthesize two donor-accept...

#7 [13.7] An Aptamer-Engineered Phenotyping System for Extracellular Vesicles Based on Honeycomb-like Melamine-Formaldehyde Microspheres and Carbon Dot Nanozymes.

Molecular phenotyping of extracellular vesicles (EVs) holds promise for noninvasive cancer diagnosis; however, current methodologies encounter limitations in cost, throughput, and sensitivity. Herein, we developed an aptamer-engineered phenotyping system designed for multiplexed, cost-effective, and user-friendly detection of EV membrane protein...

#8 [13.5] Interfacial charge engineering of Ti(3)C(2)T(x)/Bi(2)S(3) for fully integrated photoelectrochemical sensing arrays.

Developing a high-performance and fully integrated photoelectrochemical (PEC) sensing platform for the on-site detection of antibiotic residues still remains challenging, as the key lies in constructing photoactive materials and integrated electrode arrays. Herein, we introduce highly conductive and hydrophilic Ti3C2Tx MXene to engineer the inte...

#9 [13.0] Protein Binding and Molecular Size Govern Molecular Transport into Dermal Interstitial Fluid.

Dermal interstitial fluid (ISF) has emerged as the leading frontier for real-time molecular monitoring due to its rapid equilibration with blood and its role in carrying biomarkers that may reflect health status. To access ISF, we and others have developed microneedle sensor arrays, composed of microscopic probes that penetrate the epidermis pai...

#10 [13.0] Amino Acid-Programmed Biomineralization for Radical-Proximal Enzyme-MOF Interfaces in Electrochemiluminescent Influenza Hemagglutinin Sensing.

Electrochemiluminescent (ECL) biosensing is fundamentally limited by inefficient coupling between catalytic radical generation and luminophore excitation. Here, we report an amino acid-programmed biomineralization strategy for constructing radical-proximal enzyme-MOF interfaces under mild aqueous conditions. Serine reconfigures zirconium precurs...

Methodology