Aptamer 学术简报 — biosensor — 2026-06-13

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 115 篇命中（aptamer 池 227 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [21.7] Aptamer modified NPA hollow nanozymes with intrinsic peroxidase-like activity for colorimetric sensing of H1N1.

A colorimetric sensor based on aptamer-functionalized nanozyme probes was successfully developed for the sensitive and specific detection of influenza A (H1N1) virus. In this study, trimetallic nickel-palladium-gold hollow nanozymes (NPA) with excellent peroxidase (POD)-like activity were used as catalytic probes. Compared to the horseradish per...

#2 [18.9] A dual-mode electrochemiluminescence/SERS biosensor for B-type natriuretic peptide based on a T7-CRISPR/Cas13a cascade and a CsPbBr(3)@PDA@Au perovskite interface.

B-type natriuretic peptide (BNP) is an important biomarker for cardiovascular diseases, motivating sensitive and robust quantification in complex matrices. Here we report a single-electrode, anti-correlated dual-mode electrochemiluminescence/surface-enhanced Raman scattering (ECL/SERS) biosensor that couples split-aptamer recognition with a solu...

#3 [14.6] Advancing point-of-care diagnostics: Engineering and enhancing sensitivity and specificity in nanoparticle-based lateral flow assays for rapid disease detection.

Lateral flow assay (LFA) is the most widely used point-of-care (PoC) diagnostic tools due to their simplicity, rapid turnaround, portability, and low cost. Despite their extensive adoption in clinical diagnostics, food safety, and environmental monitoring, conventional LFA remain limited by inadequate sensitivity, poor quantification, and restri...

#4 [14.6] Switch-type photoelectrochemical aptasensor for microplastics and nanoplastics detection based on two-dimensional organic-inorganic heterojunction.

Microplastics and nanoplastics (MNPs) as emerging pollutants present substantial risks to both the environment and human health. Developing highly sensitive methods to rapidly identify and detect low concentrations of MNPs in complex systems remains a considerable challenge. Here, an "off-on" switch-type photoelectrochemical (PEC) aptasensor was...

#5 [14.6] Organic electrochemical transistors (OECT) based biosensors for the detection of small molecule metabolites.

Recently, organic electrochemical transistors (OECTs) have emerged as robust platforms for chemical and biological sensing, due to their intrinsic signal amplification, biocompatibility, and low-voltage functionality. OECTs have exhibited tremendous promise for detecting small molecule metabolites (SMMs), which are crucial as biomarkers in medic...

#6 [14.1] Engineered dual-fluorescence functional nucleic acid-based CRISPR/Cas12a biosensor for label-free ratiometric detection of site-specific DNA methylation.

The CRISPR/Cas12a system holds significant promise for biomedical applications. Nevertheless, the commonly used reporter, fluorophore-quencher-labeled substrates, is hindered by labor-intensive synthesis procedures and high costs, while also relying on a single-photon method and being vulnerable to environmental interference. Herein, a label-fre...

#7 [14.0] Protein Binding and Molecular Size Govern Molecular Transport into Dermal Interstitial Fluid.

Dermal interstitial fluid (ISF) has emerged as the leading frontier for real-time molecular monitoring due to its rapid equilibration with blood and its role in carrying biomarkers that may reflect health status. To access ISF, we and others have developed microneedle sensor arrays, composed of microscopic probes that penetrate the epidermis pai...

#8 [14.0] Corrigendum to "Aptamer-functionalized 2D photonic crystal hydrogels for sensitive and selective Hg(2+) detection" [J. Hazard. Mater. 511 (2026), 142176].

#9 [13.9] Exploiting conformational changes in a caffeine aptamer to engineer synthetic RNA devices.

RNA devices, including riboswitches, aptazymes, and RNA-based biosensors, have become essential components in synthetic and molecular biology. These systems make use of RNA's modularity and structural diversity to build programmable tools for sensing, regulation, and cellular computation. To drive these systems, RNA aptamers usually need to unde...

#10 [13.2] Ag-Ti(3)C(2)T(x) MXene mediated H(2)O(2) reduction for electrochemical biosensing of kanamycin in real samples based on split aptamer engineering strategy.

To resolve the conflict between multidimensional interferences derived from complex matrices and the stringent requirements for trace-level detection sensitivity, a novel electrochemical aptasensor was constructed for highly sensitive kanamycin (KANA) detection based on a split aptamer engineering strategy. Ag-Ti3C2Tx MXene, synthesized via in-s...

Methodology