Aptamer 学术简报 — biosensor — 2026-06-08

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 134 篇命中（aptamer 池 236 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [22.5] A dual-mode electrochemiluminescence/SERS biosensor for B-type natriuretic peptide based on a T7-CRISPR/Cas13a cascade and a CsPbBr(3)@PDA@Au perovskite interface.

B-type natriuretic peptide (BNP) is an important biomarker for cardiovascular diseases, motivating sensitive and robust quantification in complex matrices. Here we report a single-electrode, anti-correlated dual-mode electrochemiluminescence/surface-enhanced Raman scattering (ECL/SERS) biosensor that couples split-aptamer recognition with a solu...

#2 [17.8] Advancing point-of-care diagnostics: Engineering and enhancing sensitivity and specificity in nanoparticle-based lateral flow assays for rapid disease detection.

Lateral flow assay (LFA) is the most widely used point-of-care (PoC) diagnostic tools due to their simplicity, rapid turnaround, portability, and low cost. Despite their extensive adoption in clinical diagnostics, food safety, and environmental monitoring, conventional LFA remain limited by inadequate sensitivity, poor quantification, and restri...

#3 [17.8] Switch-type photoelectrochemical aptasensor for microplastics and nanoplastics detection based on two-dimensional organic-inorganic heterojunction.

Microplastics and nanoplastics (MNPs) as emerging pollutants present substantial risks to both the environment and human health. Developing highly sensitive methods to rapidly identify and detect low concentrations of MNPs in complex systems remains a considerable challenge. Here, an "off-on" switch-type photoelectrochemical (PEC) aptasensor was...

#4 [17.7] Engineered dual-fluorescence functional nucleic acid-based CRISPR/Cas12a biosensor for label-free ratiometric detection of site-specific DNA methylation.

The CRISPR/Cas12a system holds significant promise for biomedical applications. Nevertheless, the commonly used reporter, fluorophore-quencher-labeled substrates, is hindered by labor-intensive synthesis procedures and high costs, while also relying on a single-photon method and being vulnerable to environmental interference. Herein, a label-fre...

#5 [16.2] An electrochemical biosensing platform based on α‑iron trioxide/ferriferrous oxide magnetic nanocomposites for early diagnosis of hepatocellular carcinoma.

The detection of biologically active proteins in complex biological matrices such as serum remains challenging. To enhance the sensitivity and accuracy of detecting the hepatocellular carcinoma biomarker stress-induced phosphoprotein 1 (STIP1), we proposed a label-free "Turn-off" electrochemical aptamer-based biosensing platform without requirin...

#6 [16.2] Gold nanoparticle-modified graphene oxide electrochemical aptasensor for ultrasensitive detection of interferon gamma in kidney transplants.

The early and accurate detection of interferon gamma (IFN-γ), a key cytokine in acute cellular rejection following kidney transplantation, is essential for effective immunosuppressive management. Current methods often lack the sensitivity, speed, or simplicity for routine clinical immunomonitoring. Here, we developed a novel electrochemical apta...

#7 [13.8] Tracing Tumor-Derived Extracellular Vesicle Matrix Metalloproteinase 14 Using Dual-Target Orthogonal Barcoding-Based Microscale Thermophoretic Assays.

Longitudinal monitoring of tumor progression and metastasis provides significant benefits to improve the treatment outcome of breast cancer. Matrix metalloproteinase 14 (MMP14) on extracellular vesicles (EVs) is highly relevant to tumor invasiveness, yet the sensitivity and specificity of detection are hindered by tremendous amounts of normal EV...

#8 [13.6] Aptamer modified NPA hollow nanozymes with intrinsic peroxidase-like activity for colorimetric sensing of H1N1.

A colorimetric sensor based on aptamer-functionalized nanozyme probes was successfully developed for the sensitive and specific detection of influenza A (H1N1) virus. In this study, trimetallic nickel-palladium-gold hollow nanozymes (NPA) with excellent peroxidase (POD)-like activity were used as catalytic probes. Compared to the horseradish per...

#9 [13.6] Mg(2+)-driven triple nucleic acid cascades amplify Ru-encoded bimetallic MOF sign PFOA monitoring.

Perfluoroalkyl substances (PFAS) represent significant environmental hazards due to their exceptional persistence and propensity for bioaccumulation. However, current detection methodologies lack the ultra-trace sensitivity necessary to meet regulatory standards. In this study, we present an innovative electrochemiluminescence (ECL) aptasensor s...

#10 [13.6] A label-free fluorescent aptasensor based on DNA-templated silver nanoclusters and catalytic hairpin assembly for highly specific detection of Escherichia coli O111:B4 lipopolysaccharide.

BACKGROUND: Escherichia coli O111:B4 is an important diarrheagenic serotype and an indicator of fecal contamination in water quality monitoring. Its specific detection remains challenging because of the high structural similarity among E. coli serotypes and limitations in conventional assays. Serotype-specific lipopolysaccharide (LPS) is a stabl...

Methodology