Aptamer 学术简报 — biosensor — 2026-06-02

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 160 篇命中（aptamer 池 236 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [31.6] A dual-mode electrochemiluminescence/SERS biosensor for B-type natriuretic peptide based on a T7-CRISPR/Cas13a cascade and a CsPbBr(3)@PDA@Au perovskite interface.

B-type natriuretic peptide (BNP) is an important biomarker for cardiovascular diseases, motivating sensitive and robust quantification in complex matrices. Here we report a single-electrode, anti-correlated dual-mode electrochemiluminescence/surface-enhanced Raman scattering (ECL/SERS) biosensor that couples split-aptamer recognition with a solu...

#2 [26.8] Engineered dual-fluorescence functional nucleic acid-based CRISPR/Cas12a biosensor for label-free ratiometric detection of site-specific DNA methylation.

The CRISPR/Cas12a system holds significant promise for biomedical applications. Nevertheless, the commonly used reporter, fluorophore-quencher-labeled substrates, is hindered by labor-intensive synthesis procedures and high costs, while also relying on a single-photon method and being vulnerable to environmental interference. Herein, a label-fre...

#3 [26.6] Advancing point-of-care diagnostics: Engineering and enhancing sensitivity and specificity in nanoparticle-based lateral flow assays for rapid disease detection.

Lateral flow assay (LFA) is the most widely used point-of-care (PoC) diagnostic tools due to their simplicity, rapid turnaround, portability, and low cost. Despite their extensive adoption in clinical diagnostics, food safety, and environmental monitoring, conventional LFA remain limited by inadequate sensitivity, poor quantification, and restri...

#4 [26.6] Switch-type photoelectrochemical aptasensor for microplastics and nanoplastics detection based on two-dimensional organic-inorganic heterojunction.

Microplastics and nanoplastics (MNPs) as emerging pollutants present substantial risks to both the environment and human health. Developing highly sensitive methods to rapidly identify and detect low concentrations of MNPs in complex systems remains a considerable challenge. Here, an "off-on" switch-type photoelectrochemical (PEC) aptasensor was...

#5 [25.3] An electrochemical biosensing platform based on α‑iron trioxide/ferriferrous oxide magnetic nanocomposites for early diagnosis of hepatocellular carcinoma.

The detection of biologically active proteins in complex biological matrices such as serum remains challenging. To enhance the sensitivity and accuracy of detecting the hepatocellular carcinoma biomarker stress-induced phosphoprotein 1 (STIP1), we proposed a label-free "Turn-off" electrochemical aptamer-based biosensing platform without requirin...

#6 [25.3] Gold nanoparticle-modified graphene oxide electrochemical aptasensor for ultrasensitive detection of interferon gamma in kidney transplants.

The early and accurate detection of interferon gamma (IFN-γ), a key cytokine in acute cellular rejection following kidney transplantation, is essential for effective immunosuppressive management. Current methods often lack the sensitivity, speed, or simplicity for routine clinical immunomonitoring. Here, we developed a novel electrochemical apta...

#7 [15.0] Hydrovoltaic-photoelectric coupling effect boosted self-powered aptasensor for on-site and ultrasensitive monitoring of enrofloxacin in aquaculture products based on CdS/ZIF-67 heterojunctions.

On-site monitoring of antibiotic residues in aquaculture products is of great significance for providing instant content information to protect food safety and human health. In this work, a novel hydrovoltaic self-powered electrochemical sensor was fabricated for real-time sensitive detection of enrofloxacin (ENR) by integration of photoelectric...

#8 [13.8] SELEX-derived potassium aptamers for robust detection in a physiological sodium background.

Potassium (K+) is a vital metal in biology. So far, DNA-based potassium sensors all relied on G-quadruplex (G4) sequences that were not selected for K+ binding. Instead they were originally selected to bind thrombin, hemin or from other sources. Here, we report the first SELEX experiment to isolate DNA aptamers using K+ ions as the target. Based...

#9 [13.7] Proximity-Catalyzed In Situ Anchoring Strategy for Fluorescence-Guided Precise Delineation of Minimal Residual Disease in Breast Cancer Surgery.

Minimal residual disease (MRD) after breast cancer surgery frequently triggers tumor recurrence and metastasis, creating an urgent unmet clinical need for accurate intraoperative MRD visualization. Conventional approaches, such as intraoperative histopathology and preoperative imaging, fail to provide adequate real-time surgical guidance. Their ...

#10 [13.5] Photoelectrochemical aptasensor for ultrasensitive detection of MUC1 based on titanium dioxide/polypyrrole/carboxy polyethylene glycol hybrid anti-fouling interface.

Achieving ultrasensitive detection of MUC1 in the early stages of breast cancer is critical for reducing mortality and improving patient prognoses. Photoelectrochemical sensing has emerged as a promising technology for the detection of MUC1, primarily due to its straightforward operation and user-friendly instrumentation. However, titanium dioxi...

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