Aptamer 学术简报 — 2026-09-14

自动生成 by RBTX Aptamer Tracker v0.1。 近 14 天入库 229 篇 aptamer-related papers。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [20.1] Self-powered photoelectrochemical aptasensor based on CHA-triggered G-quadruplex/hemin cascade for homogeneous detection of ochratoxin A in a separated-coupling electrolysis system.

To address the challenge of electroactive interferences derived from complex food matrices during homogeneous photoelectrochemical (PEC) biosensing, a "separated-coupling" electrolysis platform was rationally engineered for the ultrasensitive detection of ochratoxin A (OTA). Based on the analysis of the conduction band of the α-Fe2O3 photoanode ...

#2 [19.3] Selection and validation of novel DNA aptamer panel co-specific to Plasmodium falciparum and Plasmodium ovale lactate dehydrogenase.

Malaria remains a major global health concern. The development of point-of-care diagnostic aptasensors could improve malaria detection, patient management, and eradication efforts. We selected and validated single-stranded DNA aptamers against Plasmodium falciparum lactate dehydrogenase (Pf-LDH), using systematic evolution of ligands by exponent...

#3 [18.3] A novel triple-mode sensor utilizing trimetallic derived fluorescent carbon dots nanozyme for tetracycline determination.

Tetracycline (TC) is notoriously resistant to degradation in natural environments, which contributes to its prolonged persistence and widespread contamination. Improper or excessive use of TC can lead to multifaceted hazards. In this study, we developed a trimetallic-doped carbon dots (Fe,Cu,Ce-CDs)-based composite that exhibits distinct fluores...

#4 [15.8] Electrochemically covalent lock stabilizes aptamer conformation and strengthens its sensing performance for PFOA.

PER: and polyfluoroalkyl substances (PFAS) are widely detected emerging pollutants, yet their accurate identification in complex water remains a major challenge. Herein, we developed an innovative aptamer (Apt) -based electrochemical molecularly imprinted polymer (MIP) sensor for high-sensitivity detection of perfluorooctanoic acid (PFOA) in com...

#5 [14.4] AuPt bimetallic nanocatalyst-amplified luminol-dissolved oxygen electrochemiluminescence for interferon-γ immunosensing

Interferon-γ (IFN-γ) is a pivotal inflammatory cytokine whose abnormal expression is associated with autoimmune disorders, infectious diseases, and cancer. Herein, a signal-off electrochemiluminescence (ECL) immunosensor was developed by integrating catalytic signal amplification with oriented antibody immobilization. An amino-functionalized ver...

#6 [14.0] From rational engineering of a broad-spectrum aptamer to multi-residue screening: A fluorescent aptasensor for multiplexed sulfonamides.

The increasing prevalence of multiple antibiotic residues in animal-derived foods presents significant challenges for monitoring efforts. Broad-spectrum aptamers offer great promise for enabling multiplex detection of various antibiotic residues. However, aptamers directly screened for this purpose often exhibit low affinity and poor stability, ...

#7 [14.0] Nanomaterial-enabled CRISPR-Cas biosensing for non-nucleic acid targets: Strategies, mechanisms, and applications.

Nanomaterial-assisted CRISPR-Cas biosensing has transcended nucleic acid detection, emerging as a prominent paradigm for the ultrasensitive analysis of non-nucleic acid targets. This review systematically elucidates recent advances by proposing a novel three-dimensional framework encompassing transduction efficiency, signal output, and applicati...

#8 [14.0] A bimetallic metal-organic framework-based aptasensor for dual-mode colorimetric and fluorescent detection of Fumonisin B(1).

Fumonisin B1 (FB1) is a secondary metabolite produced by Fusarium species and is considered one of the most dangerous mycotoxins. It is widely present in maize and other agricultural commodities, posing severe threats to human health and animal husbandry. Consequently, the development of a convenient and rapid detection method is of paramount im...

#9 [13.8] Aptamer recognition driven cascaded biocomputation on surface of serum-derived small extracellular vesicles

Multiplexed profiling of small extracellular vesicle (sEV) surface proteins holds promise for cancer diagnosis and prognosis due to the improved accuracy resulted from probing multiple biomarkers, yet simultaneously identifying these biomarkers on sEVs and directly reporting the analytical results remains a significant challenge. Here, we develo...

#10 [13.7] Self-Enhancing Photodynamic / Immunotherapy via a MOF Nanoplatform for Combined STING Activation and Immune Checkpoint Blockade.

Combinational photodynamic and immune checkpoint blockade (PDT/ICB) therapy is a promising approach for oncotherapy. However, the tumor microenvironment (TME) poses multiple biological barriers that can critically undermine the treatment outcomes of PDT/ICB. To this end, a cascade-amplified photodynamic immunotherapy nanoplatform based on the co...

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