Aptamer 学术简报 — 2026-07-27

自动生成 by RBTX Aptamer Tracker v0.1。 近 14 天入库 190 篇 aptamer-related papers。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [21.9] Ultrasensitive photoelectrochemical aptasensor for sulfadiazine detection enhanced by taxifolin-boosted 3D porous g-C(3)N(4).

Photoelectrochemical (PEC) sensing based on graphitic carbon nitride (g-C3N4) has promising attention due to its low background signal; however, its performance is hindered by charge carrier recombination. Herein, a high-performance PEC aptasensor was developed for ultrasensitive sulfadiazine (SDZ) detection using taxifolin-functionalized three-...

#2 [19.4] Inception-level signal amplification: Cascaded DNAzyme-Cas9 nickase achieves sub-nanomolar kanamycin tracking.

BACKGROUND: Kanamycin's persistent contamination in agricultural products poses significant human health risks due to its nephrotoxicity and bioaccumulation via the food chain. Existing methods for on-site kanamycin monitoring lack sufficient sensitivity and portability, limiting their utility in field settings. The urgent need for rapid detecti...

#3 [19.4] The integration of peptoid and phosphorothioate aptamer into electrochemical biosensors for the robust antifouling detection of prostate-specific antigen in human serum.

Electrochemical biosensors for biomarker detection in complex biological media often suffer from performance degradation. Two main causes are non-specific adsorption of biomolecules and enzymolysis of immobilized biomolecules. Consequently, the development of robust antifouling electrochemical biosensors represents an imperative research task. W...

#4 [17.6] A particle counting biosensor mediated by Clostridium butyricum argonaute for simultaneous detection of aflatoxin B(1) and ochratoxin A.

The co-contamination of aflatoxin B1 (AFB1) and ochratoxin A (OTA) in environmental foods has attracted widespread attention. A particle counting biosensor was developed for the simultaneous detection of AFB1 and OTA, utilizing polystyrene (PS) microspheres with diameters of 4 μm and 6 μm (PS4μm and PS6μm) as signal probes and aptamers as biolog...

#5 [15.6] A comprehensive review of biosensors for environmental estrogens: Design and performance.

Environmental estrogens (EEs) persist ubiquitously in the environment, posing significant threat to human health and ecosystems. Over recent decades, biosensors have emerged as pivotal tools for EEs detection, the advancement of nanomaterials and signal amplification strategies has substantially enhanced biosensor performance, enabling properly ...

#6 [15.6] Molecular filling and metal ion-mediated DNA self-assembly strategy enable evaluation of lung cancer metastasis.

Accurately assessing the risk of lung cancer metastasis is crucial for improving patient prognosis and quality of life. In this study, we developed a rapid, homogeneous fluorescence detection system (DNA-N@Ag+@PIX) for lung cancer mesenchymal circulating tumor cells (M-CTCs) based on a molecular filling strategy and metal ion-mediated DNA self-a...

#7 [15.2] Dual enzyme-mimicking Ce-UiO-66-NO(2)-driven autocatalytic cascade signal amplification for split-type electrochemical aptasensing of enrofloxacin.

Enrofloxacin (ENR) is extensively applied in veterinary medicine for controlling infectious diseases. Nevertheless, the presence of ENR residues in animal-derived food products poses considerable threats to human health. Therefore, the development of highly sensitive and accurate analytical techniques for ENR monitoring is urgently required. Her...

#8 [14.5] Detection of Point Mutation in Individual Living Circulating Malignant Cells by Targeting Molecular Beacon Delivery.

As a prevalent form of genetic alteration, single-base substitution serves as a critical determinant of targeted cancer therapeutic strategies and a driver of acquired drug resistance. Despite its clinical significance, detecting these mutations at the single-cell level remains challenging due to high costs, long analysis times, and difficulties...

#9 [14.4] Single-sequence based gFET-aptasensors for the discrimination of apo- and holo-RBP4 in human serum.

Retinol-binding protein 4 (RBP4) is a key transporter of all-trans-retinol (vitamin A), circulating in blood as either holo-RBP4 (retinol-bound) or apo-RBP4 (retinol-free). Dysregulated RBP4 levels, particularly an imbalance between apo- and holo-RBP4, have been implicated in a range of metabolic and cardiovascular diseases. Current detection me...

#10 [14.2] A versatile strategy for oligonucleotide functionalization via on-support phosphitylation

Abstract Chemically modified nucleic acids such as antisense oligonucleotides, small interfering RNA and CRISPR guide RNA have emerged as transformative modalities in modern medicine, providing new strategies for the treatment of genetic and metabolic disorders, viral infections and cancer. However, their application is limited by challenges rel...

Methodology