You ran SELEX, it enriched — but nothing bound, or truncation killed your lead. Send us the sequencing pool. We re-read it under real buffer conditions and hand back the candidates actually worth making.
The pool converged on a few high-count sequences — but the top reads don't bind, and the real binder is buried lower down.
You had a lead, minimized it, and lost the affinity — with no way to know which region actually mattered.
Full-length clustering split one binding family across dozens of clusters, so you can't tell what's really distinct.
Ship us the raw FASTQ (or a count table) and your selection buffer. NDA first if you want one.
Fold under your real Na⁺/Mg²⁺/K⁺/Ca²⁺, detect G-quadruplexes, and cluster by loop structure — not full-length sequence.
A ranked, structure-aware set of candidates, each with its conserved motif and where to truncate.
Synthesize the few worth testing — and skip the rounds you'd have wasted on look-alikes.
Not a data dump — a decision. Every candidate comes with the evidence you need to synthesize it with confidence.
Send one pool. We return a short shortlist so you can judge the value on your own data before paying anything.
Full re-analysis, complete report, and a working call to walk through the results. Priced per pool — a fraction of one wasted synthesis round.
Only us, under NDA if you'd like one signed first. Your data stays yours; we don't publish or reuse it without written permission.
The raw FASTQ (or a sequence + count table) and your selection buffer composition. That's enough to start.
We'll tell you — honestly and early. A clear "this pool won't give you a binder" saves you months, and the first look costs nothing.
Yes — that's our Discovery service. Many clients start with a Rescue, then have us run the selection or validation end-to-end.